Crystallographic studies for the chiral recognition of the novel chiral stationary phase derived from (+)-(R)-18-crown-6 tetracarboxylic acid

Chirality ◽  
1999 ◽  
Vol 11 (3) ◽  
pp. 173-178 ◽  
Author(s):  
Yoshio Machida ◽  
Hiroyuki Nishi ◽  
Kouji Nakamura
Keyword(s):  
Stationary Phase ◽  
Chiral Recognition ◽  
Chiral Stationary Phase ◽  
The Novel ◽  
Tetracarboxylic Acid

scholarly journals Synthesis of a Novel Chiral Stationary Phase by (R)-1,1′-Binaphthol and the Study on Mechanism of Chiral Recognition

Symmetry ◽  
2018 ◽  
Vol 10 (12) ◽  
pp. 704 ◽  
Author(s):  
Yongxi Wang ◽  
Dandan Liu ◽  
Yili Zhang ◽  
Yanmei Tang ◽  
Jingfeng Zhao ◽  
...  
Keyword(s):  
Stationary Phase ◽  
Chiral Recognition ◽  
Chiral Stationary Phase ◽  
Separation Mechanism ◽  
The Novel ◽  
Experimental Conditions ◽  
Element Analysis ◽  
Recognition Mechanism ◽  
New Material ◽  
Conjugated Compounds

(R)-6-Acrylic-BINOL CSP, a novel chiral stationary phase was prepared by (R)-Binaphthol (R-BINOL) by introducing the acrylic group into the 6-position of (R)-BINOL before bonding it to the surface of silica gel. The structure of the CSP was characterized by IR, SEM, and element analysis. This new material was tested for its potential as a CSP for HPLC under normal phase conditions, especially for conjugated compounds. Six solutes were chosen to evaluate the chiral separation ability of the novel CSP. The effects of the mobile phase and temperature on enantioseparation were studied, and the chiral recognition mechanism was also discussed. The results showed that the space adaptability and π-π stacking between the solutes and the CSP affected the retention and enantioseparation. The Van’t Hoff curve indicated that under the experimental conditions, the separation mechanism of six solutes did not change, which were all enthalpy driven.

Chiral Recognition Ability of an Optically Active Poly(diphenylacetylene) as a Chiral Stationary Phase for HPLC

2016 ◽  
Vol 45 (9) ◽  
pp. 1063-1065 ◽  
Author(s):  
Katsuhiro Maeda ◽  
Miyuki Maruta ◽  
Kouhei Shimomura ◽  
Tomoyuki Ikai ◽  
Shigeyoshi Kanoh
Keyword(s):  
Stationary Phase ◽  
Chiral Recognition ◽  
Chiral Stationary Phase ◽  
Optically Active ◽  
Recognition Ability

Enantiomeric separation and simulation study of eight anticholinergic drugs on an immobilized polysaccharide-based chiral stationary phase by HPLC

2018 ◽  
Vol 42 (14) ◽  
pp. 11724-11731 ◽  
Author(s):  
Meng Li ◽  
Bo Zhang ◽  
Jia Yu ◽  
Jian Wang ◽  
Xingjie Guo
Keyword(s):  
Stationary Phase ◽  
Simulation Study ◽  
Chiral Recognition ◽  
Chiral Stationary Phase ◽  
Enantiomeric Separation ◽  
Separation Process ◽  
Anticholinergic Drugs

Enantiomeric separation process of anticholinergic drugs and chiral recognition mechanisms on Chiralpak ID column.

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